Members of the CTEGD meet biweekly on Monday mornings from 8:30-9:30 to discuss the most recent and exciting research publications in the field. The focus is on molecular biology, genomics, cell biology, immunology and biochemistry of parasites and their vectors. Each session a member of the Center presents a key paper and provides additional background in the area that might be necessary to appreciate and critically analyze the new findings.

Faculty and students from outside the CTEGD are very welcome both as presenters or to just sit in on the discussion.

The CTEGD Journal Club meets in The Paul C. Coverdell Building, room 175. Coffee and bagels are provided.

If you would like to present a paper or have questions about the CTEGD Journal Club, please contact Boris Striepen at 706-583-0588 or striepen@cb.uga.edu



ScheduleToday is May 22nd, 2013
  

Past Meetings
Apr 22nd, 2013Brett Marshall presents Bougdour, A. et al. 2013. Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression. Cell Host & Microbe 13, 489-500. pdf
Apr 8th, 2013Ousman Mahmud presents Suvorova, ES, et al. 2013. Discovery of a Splicing Regulator Required for Cell Cycle Progression. PLoS Genet 9(2):e1003305. doi:10.1371/journal.pgen.10003305. pdf
Mar 25th, 2013Angela Pack presents Raetz, M. et al. 2013. Parasite-induced Th1 cells and intestinal dysbiosis cooperate in IFN-g-dependent elimination of Paneth cells. Nature Immunology 14(2): 136 - 142. pdf
Mar 4th, 2013Sivaranjani Namasivayam presents Beck, JR et al. 2013. A Toxoplasma Palmitoyl Acyl Transferase and the Palmitoylated Armadillo Repeat Protein TgARO Govern Apical Rhoptry Tethering and Reveal a Critical Role for the Rhoptries in Host Cell Invasion by Not Egress. PLoS Pathogens 9(2):e1003162. pdf
Feb 18th, 2013Briana Flaherty presents de Moraes LV, et al. 2013. Intravital Placenta Imaging Reveals Microcirculatory Dynamics Impact on Sequestration and Phagocytosis of Plasmodium-infected Erythrocytes. PLoS Pathog (9)1:e1003154 pdf
Feb 4th, 2013Hillary Danz presents Truscott, M. et al. 2013. Schistosoma mansoni Hemozoin Modulates Alternative Activation of Macrophages via Specidic Suppression of Retnla Expression and Secreation. Infect. Immun.; 81(1):133. pdf
Jan 14th, 2013Hilary Shane presents Degrandi, D. et al. 2013. Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication. PNAS; 110(1):294-299. pdf
Nov 12th, 2012John Harrington presents Koshy AA, et al. (2012) Toxoplasma Co-opts Host Cells It Does Not Invade. PLoS Pathog 8(7):e1002825. doi:10.1371/journal.ppat.1002825. pdf
Oct 29th, 2012Eldin Talundzic presents Buckee, C. O. and M. Recker. 2012. Evolution of the Multi-Domain Structures of Virulence Genes in the Human Malaria Parasite, Plasmodium falciparum. PLoS Comput Biol 8(4): e1002451. doi:10.1371/journal.pcbi.1002451 pdf
Oct 15th, 2012Tara Bracken presents Couper, KN, et al. 2012. Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation. PLoS Pathogens; 6(1): e1000744. doi:10.1371/journal.ppat.1000744 pdf
Sep 24th, 2012Demba Sarr presents Rauch, Philipp J. et al. 2012. Innate Response Activator B Cells Protect Against Microbial Sepsis. Science. 335:598-601. pdf
Sep 17th, 2012Todd Minning presents Adriano C. Coelho, et al. 2012.Multiple Mutations in Heterogeneous Miltefosine-Resistant Leishmania major Population as Determined by Whole Genome Sequencing. PLoS Negl Trop Dis. 6(2):e1512 pdf
Apr 16th, 2012Ranjani Namasivayam presents Reid, A. J. 2012. Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy. PLoS Pathogens; 8(3):e1002567. pdf
Apr 2nd, 2012Jenna Oberstaller presents Epstein, J. E. et al. 2011. Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity. Science: 334 (6055), 475-480.
pdf
Mar 19th, 2012Sharon Keller presents Yu, Y, et al. 2012. PLC-zeta causes CA2+ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P2. MBoC; 23: 371 - 380. pdf
Feb 27th, 2012Smanla Tundup presents Josefowicz, SZ, et al. 2012. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature; 482: 395-400. pdf
Feb 13th, 2012Weibo Zhang presents Barouch, DH, et al. 2012. Vaccine protection against acquisition of neutralization - resistant SIV challenges in rhesus monkeys. Nature, 482: 89 - 94. pdf
Jan 30th, 2012 Eldin Talunzic presents Tonkin M.L., et al. 2012 Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide. Science 333:463-467. pdf
Nov 14th, 2011Noelia Lander presents Pusnik, Mascha, et al. 2011. Mitochondrial Preprotein Translocase of Trypanosomatides has a Bacterial Origin. Current Biology; 21:1738-1743.
pdf
Oct 17th, 2011John Harrington presents Ghosh et al. 2011. Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut. PNAS. online ahead of print.
pdf
Oct 3rd, 2011Sarah Reiff presents Graewe, S. et al. 2011. Hostile Takeover by Plasmodium: Reorganization of Parasite and Host Cell Membranes during Liver Stage Egress. PLoS Pathogens. 7(9) e1002224. pdf
Sep 19th, 2011 pdf
Aug 22nd, 2011 pdf
May 2nd, 2011Satomi Kato presents pdf
Apr 18th, 2011Jenna Oberstaller presents Campell, T. L., et al. 2010. Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite. PLoS Pathogens; 6(10):e1001165. pdf
Mar 28th, 2011Ashley Hartley presents Ives, A. et al. 2001. Leishmania RNA Virus Controls the Severity of Mucocutaneous Leishmaniasis. Science, 331: 775 - 778. pdf
Feb 14th, 2011Kat Verbist presents Geldmacher, C. et al. 2010. Preferential infection and depletion of Mycobacterium tuberculosis - specific CD4 T cells after HIV-1 infection. J. Exp. Med. 207(13): 2869-2881. pdf
Jan 31st, 2011Demba Sarr presents Grainger, JR. et al. 2011. Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-B pathway. J. Exp. Med., 207(11): 2331-2341. pdf
Dec 6th, 2010Sharon Keller presents Vincent IM, et al. 2010. A Molecular Mechanism for Eflornithine Resistance in African Trypanosomes. PLoS Pathogens, 6(11) e1001204. pdf
Nov 1st, 2010Noelia Lander presents Szoor B., et al. 2010. A novel phosphatase cascade regulates differentiation in Trypansoma brucei via a glycosomal signaling pathway. Genes & Development, 24: 1306 - 1316. pdf
Oct 18th, 2010TBA pdf
Oct 4th, 2010TBA pdf
Sep 20th, 2010Demba Sarr presents Amante FH, et al. 2010. Immune-Mediated Mechanisms of Parasite Tissue Sequestration during Experimental Cerebral Malaria. The Journal of Immunology, 185: epublished. pdf
Aug 23rd, 2010TBA pdf
Apr 26th, 2010TBA pdf
Apr 12th, 2010Veronica Jimenez presents Chuenova MV, et al. 2009. Trypansoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategy. Science Signaling; 2(97): 1-9. pdf
Mar 29th, 2010TBA pdf
Mar 15th, 2010Ashley Hartley presents Shaw MH, et al. 2009. T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii. Nature Immunology; 10: 1267 - 1274. pdf
Feb 22nd, 2010TBA pdf
Feb 8th, 2010Kat Verbist presents Boddey JA, et al. 2010. An aspartyl protease directs malaria effector proteins to the host cell. Nature; 463:627-631. pdf
Jan 25th, 2010Sharon Keller presents Thomson R, et al. 2009 Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes. PNAS; 106(46): 19509-19514. pdf
Nov 30th, 2009Jamie Winternitz presents Latorre-Margalef N, et al. 2009. Effects of influenza A virus infection on migrating mallard ducks. Proc. R. Soc. B; 276: 1029-1036. pdf
Nov 9th, 2009Doug Pace presents de Koning-Ward TF, et al. 2009 A newly discovered protein export machine in malaria parasites. Nature; 459:945-949. pdf
Oct 26th, 2009Jenna Oberstaller presents Rich, SM, et al. 2009. The origin of malignant malaria. PNAS, 106(35): 14902-14907. pdf
Oct 12th, 2009Jay Avery presents Yost CC, Cody MJ, Harris ES, Thornton NL, McInturff AM, Martinez ML, et al. Impaired neutrophil extracellular trap (NET) formation: a novel
innate immune deficiency of human neonates. Blood. 2009
Jun;113(25):6419-27 pdf
Sep 21st, 2009Josh Cole
pdf
Aug 31st, 2009Sethu Nair presents Kafsack BGC, et al. 2009. Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells. Science; 323:530-533. pdf
Apr 27th, 2009Simon Odera pdf
Apr 13th, 2009Jeremy DeBarry presents Pritham EJ, et al. 2007. Mavericks, a novel class of giant transposable elements widespread in eukaryotes and related to DNA virsuses. GENE. 390:3-17. pdf
Mar 30th, 2009Rachel Donaldson pdf
Mar 16th, 2009No presenter pdf
Feb 23rd, 2009Tiffany Weinkopff presents Sutton, T.L., et al. 2008. Anti-inflammatory mechanisms of enteric Heligmosomoides polygyrus infection against trinitrobenzene sulfonic acid-induced colitis in a murine model. Infection and Immunity. 76(10): 4772-4782. pdf
Feb 9th, 2009Presenter TBA pdf
Jan 26th, 2009Katherine Verbist presents Davis, J.M. and L. Ramakrishnan. 2009. The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection. Cell; 136:37-49. pdf
Dec 8th, 2008Presenter TBA
pdf
Nov 17th, 2008Charles Rosenberg presents Lundle RJ, et al. 2008. Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8a+ dendritic cells. PNAS; 105(38):14509-14514. pdf
Nov 3rd, 2008Sarah Reiff presents Milman N. et al. 2007. Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes. PNAS; 104(49): 19250-19255.
  pdf
Oct 20th, 2008Josh Cole presents Dunay IR, et al. 2008. Gr1+ Inflammatory Monocytes are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii. Immunity; 29:306-317.
pdf
Oct 6th, 2008Demba Sarr presents Couper KN, et al. 2008. IL-10 from CD4+CD25-Foxp3-CD127- Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection. PLoS Pathogens; 4(2):e1000004. pdf
Sep 22nd, 2008No Presenter pdf
Sep 8th, 2008No Presenter pdf
Apr 14th, 2008Paul Ulrich Wilkinson SR, et al. 2008. A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. PNAS 105:5022-5027. pdf
Mar 24th, 2008Demba Sarr Wykes MN, et al. 2007. Plasmodium Strain Determines Dendritic Cell Function Essential for Survival from Malaria. PLoS Pathogens; 3(7):904-912. pdf
Mar 17th, 2008Sethu Nair Singh AP. 2007 Plasmodium Circumsporozoite Protein Promotes the Development of the Liver Stages of the Parasite. Cell; 131: 492-504. pdf
Feb 25th, 2008Tiffany Weinkopff Yeoh S. et al. 2007. Subcellular Discharge of a Serine Protease Mediates Release of Invasive Malaria Parasites from Host Erythrocytes. Cell. 131: 1072-1083. pdf
Feb 11th, 2008Carla Black Berhe N. et al. 2007. Intensity of Schistosoma mansoni, Hepatitis B, Age, and Sex Predict Levels of Hepatic Periportal Thickening/Fibrosis (PPT/F): A Large-Scale Community-based Study in Ethiopia. Am. J. Trop. Med. Hyg. 77(6): 1079-1086. pdf
Jan 28th, 2008Josh Cole Wolf AJ, et al. 2008. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. JEM; 205(1):105-115. pdf
Nov 26th, 2007Abhijit Bakre Bringaud F. et al. 2007. Members of a large Retroposon family are determinants of post-transcriptional gene expression in Leishmania. PLoS Pathog.;3(9):1291-307. pdf
Nov 12th, 2007Charles Rosenberg Goldszmid RS, et al. 2007. TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production.J. Exp. Med. 204: 2591-2602. pdf
Oct 22nd, 2007Sethu Nair Biswas AK, et al. 2007. Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endotherlium and for platelet-mediated clumping. PLoS Pathogens; 3(9): 1271 - 1280. pdf
Oct 8th, 2007Don Champagne Donovan MJ, et al. 2007. Uninfected Mosquito Bites Confer Protection against Infection with Malaria Parasites. Infection & Immunity; 75(5): 2523-2530. pdf
Sep 24th, 2007Demba Sarr Muehlenbachs A, et al. 2007. Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infections. The Journal of Immunology; 179: 557-565. pdf
Sep 10th, 2007Diana Martin Nagase H, et al. 2007. Despite Increased CD4+Foxp3+ Cells within the Infection Site, BALB/c IL-4 Receptor-Deficient Mice Reveal CD4+Foxp3-Negative T cells as a Source of IL-10 on Leishmania major Susceptibility. Journal of Immunology; 179:2435-2444. pdf
Apr 23rd, 2007Abhijeet Bakre Saeij JP, et al. 2006. Polymorphic Secreted Kinases are Key Virulence Factors in Toxoplasmosis. Science; 314: 1780-1783. AND Taylor S, et al. 2006. A Secreted Serine-Threonin Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii. Science; 314: 1776-1780. pdf
Apr 16th, 2007Lisa Bixby Ling YM, et al. 2006. Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. JEM; 203(9): 2063 - 2071. pdf
Apr 2nd, 2007Laura Cliffe Zaph C, et al. 2007. Epithelial-cell-intrinsic IKK-B expression regulates intestinal immune homeostasis. Nature; Epublished Feb. 25. pdf
Mar 19th, 2007Andrea Pruijssers Dunne EF, et al. 2007. Prevalence of HPV infection among females in the United States. JAMA; 297(8):813-819. pdf
Mar 5th, 2007Christie Harwell Awandare GA, et al. 2007. Role of Monocyte-Acquired Hemozoin in Suppression of Macrophage Migration Inhibitory Factor in Children with Severe Malarial Anemia. IAI; 75(1):201-210. pdf
Feb 19th, 2007Tiffany Weinkopff Yurchenko E, et al. 2006. CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence. JEM; 203(11):2451-2460. pdf
Feb 5th, 2007Roberto Docampo Piacenza L, et al. 2006. Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial Fe-superoxide dismutase overexpression. Biochemical Journal. AND Prathalingham SR, et al. 2007. Deletion of the Trypanosoma brucei Superoxide Dismutase Gene sodb1 Increases Sensitivity to Nifurtimox and Benznidazole. Anitmicrobial Agents and Chemotherapy; 51(2):755-758. pdf1 pdf2 pdf
Jan 22nd, 2007Carla Black Atika, B. et al. 2006. Impact of Annual Targeted Treatment on Infectious Trachoma and Susceptibility to Reinfection. JAMA; 296(12):1488-1497 pdf
Jan 8th, 2007 pdf
Dec 4th, 2006Charles Rosenberg Cobb BS, et al. 2006. A role for Dicer in immune regulation. J. Exp. Med. 203:2519-2527 pdf
Nov 20th, 2006Angel Padilla Bertholet S, et al. 2006. Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo. J Immunol. 177: 3525-3533 pdf
Nov 6th, 2006David Peterson Mair GR, et al. 2006. Regulation of Sexual Development of PLASMODIUM by Translation Repression. Science; 313: 667-669. pdf
Oct 23rd, 2006Sethu Nair Felix Yarovinsky et al. Toll-like Receptor Recognition Regulates Immunodominance in an Antimicrobial CD4+ T Cell Response, IMMUNI (2006), doi:10.1016/j.immuni.2006.07.015 pdf
Oct 9th, 2006Matthew Collins Singh SB, et al. 2006. Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria. Science; 313:1438-1441. pdf
Sep 25th, 2006Silvia Moreno Soo Hee Lee, et al. 2006. Fatty Acid Synthesis by Elongases in Trypanosomes. Cell; 126:691-699. pdf
Sep 11th, 2006Juan Bustamante Baral TN, et al. 2006. Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor. Nature Medicine; 12(5): 580-584. pdf
Aug 28th, 2006Jan Schwenkenbecher Lehmann T. et al. 2006. Globalization and the population structure of Toxoplasma gondii. PNAS; 103(30):11423-11428. pdf
May 1st, 2006Sethu Nair Baumeister S. et al. 2006. Evidence for the involvement of Plasmodium falciparum proteins in the formation of new permeability pathways in the erythrocyte membrane. Molecular Microbiology; 60(2): 493-504. pdf
Apr 17th, 2006Lisa Bixby Polley R. et al. 2005. Chronic Leishmania donovani Infection Promotes Bystander CD8+ T-cell Expansion and Heterologous Immunity. Infection and Immunity; 72(2): 7996-8001. pdf
Apr 3rd, 2006Charles Rosenberg Tumpey, TM. 2005. Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice. Journal of Virology; 79(23):14933-14944. pdf
Mar 20th, 2006Dan Xu Suffia IJ, et al. 2006. Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens. JEM. 203(3):early release. pdf
Mar 6th, 2006Anja T. R. Jensen SPECIAL SEMINAR: "Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by Group A var genes" pdf
Feb 20th, 2006Carly Jordan Molestina RE and AP Sinai. 2005. Host and parasite-derived ILL activities direct distinct temporal phases of NF-kB activation and target gene expression following Toxoplasma gondii infection. Journal Cell Science 118:5785-5796. pdf
Feb 6th, 2006Tiffany Weinkopff Dann SM, et al. 2005. Interleukin-15 Activates Human Natural Killer Cells to Celar the Intestinal Protozoan Cryptosporidium. JID 192:1294-1302. pdf
Jan 23rd, 2006Diana Martin Baum, J. et al. 2005. Invasion by P. falciparum Merozoites Suggests a Hierarchy of Molecular Interactions. PLoS Pathogens, 1(4)e37:299-309. pdf
Jan 9th, 2006Boris Striepen pdf
Dec 5th, 2005Jessica Kissinger Martens S, et al. 2005. Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases. PLoS Pathogens; 1(3)e24:0187-0201. pdf
Nov 21st, 2005Giel van Dooren Li W, et al. 2005. Yeast model uncovers dual roles of mitochondria in the action of artemisinin. PLoS Genetics, 1(3):e36. pdf
Nov 7th, 2005Nandita Mullapudi Callebaut I, et al. 2005. Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes. BMC Genomics; 6(100): 1-20. pdf
Oct 24th, 2005Naomi Lucchi Chamekh M, et al. 2005. Transfection of Trypanosoma cruzi with Host CD40 Ligand Results in Improved Control of Parasite Infection. Infection and Immunity, 73(10):6552-6561. pdf
Oct 10th, 2005Valerie Gordon Kariminia A, et al. 2005. Transforming Growth Factor B1 Production by CD4+ CD25+ Regulatory T Cells in Peripheral Blood Mononuclear Cells from Healthy Subjects Stimulated with Leishmania guyanensis. Infection and Immunity; 73(9): 5908-5914. pdf
Sep 26th, 2005Matt Collins Bian, KA, et al. 2005. Helminth regulation of host IL-4Ra/Stat6 signaling: Mechanism underlying NOS-2 inhibition by Trichinella spiralis. PNAS, 702 (11): 3036-3041. pdf
Sep 12th, 2005Rick Tarleton Stober CB, et al. IL-10 from Regulatory T Cells Determines Vaccine Efficacy in Murine Leishmania major Infection. J Immunol. 2005 Aug 15;175(4):2517-24. AND Wykes MN, et al. Plasmodium yoelii Can Ablate Vaccine-Induced Long-Term Protection in Mice. J Immunol. 2005 Aug 15;175(4):2510-6. pdf
Aug 29th, 2005Shipra Vaishnava Ramamoorthi N. et al. 2005. The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature; 436: 573-577. pdf
Apr 18th, 2005Marc-Jan Gubbels Charron AJ and LD Sibley. 2004. Molecular Partitioning during Host Cell Penetration by Toxoplasma gondii. Traffic; 5:855-867. pdf
Apr 4th, 2005Lisa Sharling Figueiredo LM , et al. (2005) The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus. Nucleic Acids Research; 33(3):1111-1122. pdf
Mar 21st, 2005Josh Kotner Mueller, AK, et al. 2005. Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature, 433: 164-167. pdf
Mar 7th, 2005Jessica Kissinger Loftus B, et al. 2005. The genome of the protist parasite Entamoeba histolytica. Nature, 433: 865-868. pdf
Feb 21st, 2005Jayakumar Poovassery Brustoski K, et al. 2005. IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria. Journal of Immunology, 175:1738-1745. pdf
Feb 7th, 2005Jolly Mazumdar Hiller NL, et al. 2004. A Host-Targeting Signal in Virulence Proteins Reveals a Secretome in Malarial Infection. Science;306:1934-1937. pdf
Jan 24th, 2005Dan Colley Oriss TB, et al. 2005. Dynamics of Dendritic Cell Phenotype and Interactions with CD4+ T Cells in Airway Inflammation and Tolerance. J. Immunol.;174:854-863. pdf
Jan 10th, 2005Diana Martin Coban C, et al. 2005. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. JEM. 201(1):19-25. pdf
Dec 6th, 2004Boris Striepen Engstler M and M Boshart. 2004. Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei. Genes & Development, 18:2798-2811. pdf
Nov 22nd, 2004Rick Tarleton Nitz N, et al. 2004. Heritable Integration ofkDNA Minicircle Sequences from Trypanosoma cruzi in to the Avian Genome: Insights into Human Chagas Disease. Cell, 118:175-186. pdf
Nov 8th, 2004Nandita Mullapudi Coulson RMR, et al. 2004. Comparative genomics of transcriptional control in the human malaria parasite Plasmodium falciparum. Genome Research, 14: 1548-1554. pdf
Oct 25th, 2004David Peterson Gamain B, et al. 2004. Identification of a 67-amino-acid region of the Plasmodium falciparum variant surface antigen that binds chondroitin sulphate A and elicits antibodies reactive with the surface of placental isolates. Molecular Microbiology, 53(2): 445-455. pdf
Oct 11th, 2004Becky Bundy Koski G, et al. 2004. Cutting Edge: Innate immune aystem discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells. Journal of Immunology. 172:3989-3993. pdf
Sep 27th, 2004Marc-Jan Gubbels Blandin S, et. al. 2004. Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae. Cell, 116: 661-670. pdf
Sep 13th, 2004Naomi Lucchi Pouniotis DS, et al. 2004. Dendritic cells induce immunity and long-lasting protection against blood-stage malaria despite an in vitro parasite-induced maturation defect. Infection and Immunity, 72(9): 5331-5339 pdf
Apr 19th, 2004Jinling Huang Osta MA, et al. 2004.Effects of Mosquito Genes on Plasmodium Development. Science, 303: 2030-2032. pdf
Apr 5th, 2004Naomi Lucchi Cockburn IA, et al. 2004. A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria. PNAS, 101(1): 272-277. pdf
Mar 22nd, 2004Dan Colley Cervi L, et al. Cutting Edge: Dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific TH2 repsonses. J.Immunol. 2004 Feb 15;172(4):3016-20. pdf
Feb 23rd, 2004Diana Martin Moody DB, et al. 2004. T Cell Activation by Lipopeptide Antigens. Science, 303:527-531 pdf
Feb 9th, 2004Jayakumar Poovassery Fallarino F, et al. 2003. Modulation of tryptophan catabolosm by regulatory T cells. Nature Immunology, 4(12): 1206-1212. pdf
Jan 26th, 2004Marc-Jan Gubbels Coppens I and KA Joiner. 2003. Host but not parasite cholesterol controls Toxoplasma cell entry by modulating organelle discharge. Molecular Biology of the Cell, 14:3804-3820. pdf
Jan 12th, 2004Shipra Vaishnava Relict mitochondrions of Giardia and Cryptosporidium pdf
Dec 1st, 2003Josh Kotner Vanhamme L, et al. 2003. Apolipoprotein L-1 is the trypanosome lytic factor of human serum. Nature, 422:83-87. pdf
Nov 17th, 2003Jessica Kissinger Dueling Techniques - The Plasmodium transcriptome revealed (part II) pdf
Nov 3rd, 2003Nandita Mullapudi Dueling Techniques - The Plasmodium transcriptome revealed (part I) pdf
Oct 20th, 2003Rick Tarleton Yan Shi et al. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature, 425: 516-521. pdf
Oct 6th, 2003Becky Bundy Doench JG, et al. 2003. siRNAs can function as miRNAs. Gene & Development, 17:438-442. pdf
Sep 22nd, 2003Kanji Watanabe Miniature pigs as a highly susceptible experimental model for Schistosoma japonicum infection pdf
Sep 8th, 2003David Morrison U. Eckstein-Ludwig, et al. 2003. Artemisinins target the SERCA of Plasmodium falciparum. Nature, 424: 957-961. pdf
Aug 25th, 2003Julie Moore David McDonald, et al. 2003. Recruitment of HIV and its receptors to dendritic cell-T-cell junctions. Science, 300:1295-1297 pdf
Apr 21st, 2003Becky Bundy Serikawa KA, et al. (2003) The transcriptome and its translation during recovery from cell-cycle arrest in Saccharomyces cerevisiae. MCP papers in press. pdf
Apr 7th, 2003Chitra Thadhani Stedman TT, et al. Toxoplasma gondii Rab6 Mediates a Retrograde Pathway for Sorting of Constitutively Secreted Proteins to the Golgi Complex. Journal of Biological Chemistry, 14 Feb 2003;278(7):5433-5 pdf
Mar 24th, 2003Alison Nairn Gaunt MW, et al. Mechanism of genetic exchange in American trypanosomes. Nature, 27 Feb 2003;421:936-939 pdf
Mar 10th, 2003Paul Drummond Miller SK, et al. A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle. J. of Biological Chemistry, 6 Dec 2002;277(49):47524-47532 pdf
Feb 24th, 2003Jayakumar Poovassery Hannaert V, et al. Plant-like traits associated with metabolism of Trypanosoma parasites. PNAS, Feb. 2003;100(3):1067-1071 pdf
Feb 10th, 2003Jennifer Gibson Huston CD, et al. Apoptotic Killing and Phagocytosis of Host Cells by the Parasite Entamoeba histolytica. Infection and Immunity, Feb 2003;71(2):964-972. pdf
Jan 27th, 2003Diana Martin Amelie v. Saint Andre, et al. The Role of Endosymbiotic Wolbachia Bacteria in the Pathogenesis of River Blindness. 8 March 2002;295:1892-1895. pdf
Jan 13th, 2003Naomi Lucchi Greenbaum, DC. et al. A Role for the Protease Falcipain 1 in Host Cell Invasion by the Human Malaria Parasite. Science, 6 December 2002;298:2002-2006 pdf
Dec 2nd, 2002Nandita Mullapudi pdf
Nov 18th, 2002Shipra Vaishnava Meissner M, et. al. Role of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasion. Science. 2002 Oct 25;298(5594):837-40 pdf
Nov 4th, 2002Jessica Kissinger Gardner MJ, et al. Genome squence of the human malaria parasite Plasmodium falciparum. Nature, 2002;v 419:498-511 pdf
Oct 21st, 2002Marc-Jan Gubbels Mann T, et al. Proteolytic processing of TgMC1 during maturations of the membrane skeleton of Toxoplasma gondii. Paper in press: J. Biol. Chem. August 12, 2002 pdf
Oct 7th, 2002Dan Colley Jung, Steffen et.al. In Vivo Depletion of CD11c+ Dendritic Cells Abrogates Priming of CD8+ T Cells by Exogenous Cell-Associated Antigens. Immunity, Vol. 17, 211-220, August,2002 pdf
Sep 9th, 2002Rick Tarleton Flodstrom M, et al. Target cell defense prevents the development of diabetes after viral infection. pdf
Aug 26th, 2002Boris Striepen pdf
Dec 17th, 2001Dan Colley Davies, S.J., Grogran, J.L., Blank, R.B., Line, K.C., Locksley, R.M., McKerrow, J.H. "Modulations of blood fluke development in the liver by hepatic CD4+ Lymphocytes." pdf
Dec 3rd, 2001Boris Striepen Wickham, M.E., Rug, M., Ralph, S.A., Klonis, N., McFadden, G.I., Tilley, L., Cowman, A.F. "Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes." pdf
Nov 19th, 2001Christine Wasunna Bastin, P., Ellis, K., Kohl, L., Gull, K. "Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system." pdf
Nov 5th, 2001Sudesh Kumar Venezuela et al. "Towards a Defined Anti-Leishmania Vaccine Targeting Vector Antigens: Characterization of a Protective Salivary Protein." pdf
Oct 22nd, 2001Julie Moore Flick, K., Scholander, C., Chen, Q., Fernandez, V., Pouvella, B., Gysin, J., Wahlgren, M. "Role of nonimmune IgG bound to PfEMP1 in placental malaria." pdf
Oct 8th, 2001Jennifer Kraft Masopust, D., Vezys, V., Marzo, A.L., Lefrancois, L. "Preferential localization of effector memory cells in nonlymphoid tissue." pdf
Sep 24th, 2001Ray Kaplan Dent, J.A., Smith, M.M., Vassilatis, D.K., Avery, L. "The genetics of ivermectin resistance in Caenorhabditis elegans." pdf
Sep 10th, 2001Jolly Mazumdar Hakansson, S., Charron, A.J., Sibley, L.D. "Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacoule." pdf
Aug 20th, 2001Kara Cummings Schnaufer, A., Panigrahi, A.K., Panicucci, B., Igo, R.P., Salavati, R., Stuart, K. "An RNA ligase essentail for RNA editing and survival of the bloodstream form of Trypanosoma brucei." pdf
Mar 26th, 2001Don Champagne Han, Y.S., Thompson, J., Kafatos, F.C., Barillas-Mury, C. "Molecular interactions between Anopheles stephensi midgut cells and Plasmodium berghi: the time bomb theory of ookinete invasion of mosquitos pdf
Feb 19th, 2001Julie Moore M. Mota, et al. "Migration of Plasmodium sporozoites through cells before infection." pdf
Feb 5th, 2001Diana Martin Salter, et al. "Schistosome invasion of human skin and degradation of dermal elastin are mediated by a single serine protease." pdf
Jan 22nd, 2001Katya Ledin Kamhawi, S., Belkaid, Y., Modi, G., Rowton, E., Sacks, D. "Protection against cutaneous leishmaniasis resulting from bites of uninfected sand flies." pdf
Jan 8th, 2001Julie Dagremond Ilg, T. "Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana." pdf
Dec 18th, 2000Bolyn Hubby Wang, Morris, Drew, Englund. "RNA interference in Trypanosoma brucei." and LaCount, D.J., Bruse, S., Hill, K.L., Donelson, J.E. "Double-stranded RNA interferrence in Trypanosoma brucei pdf
Dec 4th, 2000David Peterson Freitas-Junior, L.H., Bottius, E., Pirrit, L.A., Deitsch, K.W., Scheidig, C., Guniet, F., Nehrbass, U., Wellems, T.E., Scherf, A. "Frequent ectopic recombination of virulence factor genes in telomeri pdf
Nov 20th, 2000Rick Tarleton Kedl, R.M., Rees, W.A., Hildeman, D.A., Schaefer, B., Mitchell, T., Kappler, J., Marrack, P. "T cells compete for access to antigen-bearing antigen-presenting cells." pdf
Nov 6th, 2000Boris Striepen Desai, S.A., Bezrukov, S.M., Zimmerberg, J. "A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite." pdf
Dec 31st, 1969TBA pdf