Members of the CTEGD meet biweekly on Monday mornings from 8:30-9:30 to discuss the most recent and exciting research publications in the field. The focus is on molecular biology, genomics, cell biology, immunology and biochemistry of parasites and their vectors. Each session a member of the Center presents a key paper and provides additional background in the area that might be necessary to appreciate and critically analyze the new findings.
Faculty and students from outside the CTEGD are very welcome both as presenters or to just sit in on the discussion.
The CTEGD Journal Club meets in The Paul C. Coverdell Building, room 175. Coffee and bagels are provided.
If you would like to present a paper or have questions about the CTEGD Journal Club, please contact Boris Striepen at 706-583-0588 or striepen@cb.uga.edu
| Schedule | Today is May 22nd, 2013 |
|   |   |
| Past Meetings | |
| Apr 22nd, 2013 | Brett Marshall presents Bougdour, A. et al. 2013. Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression. Cell Host & Microbe 13, 489-500. pdf |
| Apr 8th, 2013 | Ousman Mahmud presents Suvorova, ES, et al. 2013. Discovery of a Splicing Regulator Required for Cell Cycle Progression. PLoS Genet 9(2):e1003305. doi:10.1371/journal.pgen.10003305. pdf |
| Mar 25th, 2013 | Angela Pack presents Raetz, M. et al. 2013. Parasite-induced Th1 cells and intestinal dysbiosis cooperate in IFN-g-dependent elimination of Paneth cells. Nature Immunology 14(2): 136 - 142. pdf |
| Mar 4th, 2013 | Sivaranjani Namasivayam presents Beck, JR et al. 2013. A Toxoplasma Palmitoyl Acyl Transferase and the Palmitoylated Armadillo Repeat Protein TgARO Govern Apical Rhoptry Tethering and Reveal a Critical Role for the Rhoptries in Host Cell Invasion by Not Egress. PLoS Pathogens 9(2):e1003162. pdf |
| Feb 18th, 2013 | Briana Flaherty presents de Moraes LV, et al. 2013. Intravital Placenta Imaging Reveals Microcirculatory Dynamics Impact on Sequestration and Phagocytosis of Plasmodium-infected Erythrocytes. PLoS Pathog (9)1:e1003154 pdf |
| Feb 4th, 2013 | Hillary Danz presents Truscott, M. et al. 2013. Schistosoma mansoni Hemozoin Modulates Alternative Activation of Macrophages via Specidic Suppression of Retnla Expression and Secreation. Infect. Immun.; 81(1):133. pdf |
| Jan 14th, 2013 | Hilary Shane presents Degrandi, D. et al. 2013. Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication. PNAS; 110(1):294-299. pdf |
| Nov 12th, 2012 | John Harrington presents Koshy AA, et al. (2012) Toxoplasma Co-opts Host Cells It Does Not Invade. PLoS Pathog 8(7):e1002825. doi:10.1371/journal.ppat.1002825. pdf |
| Oct 29th, 2012 | Eldin Talundzic presents Buckee, C. O. and M. Recker. 2012. Evolution of the Multi-Domain Structures of Virulence Genes in the Human Malaria Parasite, Plasmodium falciparum. PLoS Comput Biol 8(4): e1002451. doi:10.1371/journal.pcbi.1002451 pdf |
| Oct 15th, 2012 | Tara Bracken presents Couper, KN, et al. 2012. Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation. PLoS Pathogens; 6(1): e1000744. doi:10.1371/journal.ppat.1000744 pdf |
| Sep 24th, 2012 | Demba Sarr presents Rauch, Philipp J. et al. 2012. Innate Response Activator B Cells Protect Against Microbial Sepsis. Science. 335:598-601. pdf |
| Sep 17th, 2012 | Todd Minning presents Adriano C. Coelho, et al. 2012.Multiple Mutations in Heterogeneous Miltefosine-Resistant Leishmania major Population as Determined by Whole Genome Sequencing. PLoS Negl Trop Dis. 6(2):e1512 pdf |
| Apr 16th, 2012 | Ranjani Namasivayam presents Reid, A. J. 2012. Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy. PLoS Pathogens; 8(3):e1002567. pdf |
| Apr 2nd, 2012 | Jenna Oberstaller presents Epstein, J. E. et al. 2011. Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity. Science: 334 (6055),
475-480. |
| Mar 19th, 2012 | Sharon Keller presents Yu, Y, et al. 2012. PLC-zeta causes CA2+ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P2. MBoC; 23: 371 - 380. pdf |
| Feb 27th, 2012 | Smanla Tundup presents Josefowicz, SZ, et al. 2012. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature; 482: 395-400. pdf |
| Feb 13th, 2012 | Weibo Zhang presents Barouch, DH, et al. 2012. Vaccine protection against acquisition of neutralization - resistant SIV challenges in rhesus monkeys. Nature, 482: 89 - 94. pdf |
| Jan 30th, 2012 | Eldin Talunzic presents Tonkin M.L., et al. 2012 Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide. Science 333:463-467. pdf |
| Nov 14th, 2011 | Noelia Lander presents Pusnik, Mascha, et al. 2011. Mitochondrial Preprotein Translocase of Trypanosomatides has a Bacterial Origin. Current Biology; 21:1738-1743. |
| Oct 17th, 2011 | John Harrington presents Ghosh et al. 2011. Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut. PNAS. online ahead of print. |
| Oct 3rd, 2011 | Sarah Reiff presents Graewe, S. et al. 2011. Hostile Takeover by Plasmodium: Reorganization of Parasite and Host Cell Membranes during Liver Stage Egress. PLoS Pathogens. 7(9) e1002224. pdf |
| Sep 19th, 2011 | |
| Aug 22nd, 2011 | |
| May 2nd, 2011 | Satomi Kato presents pdf |
| Apr 18th, 2011 | Jenna Oberstaller presents Campell, T. L., et al. 2010. Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite. PLoS Pathogens; 6(10):e1001165. pdf |
| Mar 28th, 2011 | Ashley Hartley presents Ives, A. et al. 2001. Leishmania RNA Virus Controls the Severity of Mucocutaneous Leishmaniasis. Science, 331: 775 - 778. pdf |
| Feb 14th, 2011 | Kat Verbist presents Geldmacher, C. et al. 2010. Preferential infection and depletion of Mycobacterium tuberculosis - specific CD4 T cells after HIV-1 infection. J. Exp. Med. 207(13): 2869-2881. pdf |
| Jan 31st, 2011 | Demba Sarr presents Grainger, JR. et al. 2011. Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-B pathway. J. Exp. Med., 207(11): 2331-2341. pdf |
| Dec 6th, 2010 | Sharon Keller presents Vincent IM, et al. 2010. A Molecular Mechanism for Eflornithine Resistance in African Trypanosomes. PLoS Pathogens, 6(11) e1001204. pdf |
| Nov 1st, 2010 | Noelia Lander presents Szoor B., et al. 2010. A novel phosphatase cascade regulates differentiation in Trypansoma brucei via a glycosomal signaling pathway. Genes & Development, 24: 1306 - 1316. pdf |
| Oct 18th, 2010 | TBA pdf |
| Oct 4th, 2010 | TBA pdf |
| Sep 20th, 2010 | Demba Sarr presents Amante FH, et al. 2010. Immune-Mediated Mechanisms of Parasite Tissue Sequestration during Experimental Cerebral Malaria. The Journal of Immunology, 185: epublished. pdf |
| Aug 23rd, 2010 | TBA pdf |
| Apr 26th, 2010 | TBA pdf |
| Apr 12th, 2010 | Veronica Jimenez presents Chuenova MV, et al. 2009. Trypansoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategy. Science Signaling; 2(97): 1-9. pdf |
| Mar 29th, 2010 | TBA pdf |
| Mar 15th, 2010 | Ashley Hartley presents Shaw MH, et al. 2009. T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii. Nature Immunology; 10: 1267 - 1274. pdf |
| Feb 22nd, 2010 | TBA pdf |
| Feb 8th, 2010 | Kat Verbist presents Boddey JA, et al. 2010. An aspartyl protease directs malaria effector proteins to the host cell. Nature; 463:627-631. pdf |
| Jan 25th, 2010 | Sharon Keller presents Thomson R, et al. 2009 Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes. PNAS; 106(46): 19509-19514. pdf |
| Nov 30th, 2009 | Jamie Winternitz presents Latorre-Margalef N, et al. 2009. Effects of influenza A virus infection on migrating mallard ducks. Proc. R. Soc. B; 276: 1029-1036. pdf |
| Nov 9th, 2009 | Doug Pace presents de Koning-Ward TF, et al. 2009 A newly discovered protein export machine in malaria parasites. Nature; 459:945-949. pdf |
| Oct 26th, 2009 | Jenna Oberstaller presents Rich, SM, et al. 2009. The origin of malignant malaria. PNAS, 106(35): 14902-14907. pdf |
| Oct 12th, 2009 | Jay Avery presents Yost CC, Cody MJ, Harris ES, Thornton NL, McInturff AM, Martinez ML, et al. Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates. Blood. 2009 Jun;113(25):6419-27 pdf |
| Sep 21st, 2009 | Josh Cole |
| Aug 31st, 2009 | Sethu Nair presents Kafsack BGC, et al. 2009. Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells. Science; 323:530-533. pdf |
| Apr 27th, 2009 | Simon Odera pdf |
| Apr 13th, 2009 | Jeremy DeBarry presents Pritham EJ, et al. 2007. Mavericks, a novel class of giant transposable elements widespread in eukaryotes and related to DNA virsuses. GENE. 390:3-17. pdf |
| Mar 30th, 2009 | Rachel Donaldson pdf |
| Mar 16th, 2009 | No presenter pdf |
| Feb 23rd, 2009 | Tiffany Weinkopff presents Sutton, T.L., et al. 2008. Anti-inflammatory mechanisms of enteric Heligmosomoides polygyrus infection against trinitrobenzene sulfonic acid-induced colitis in a murine model. Infection and Immunity. 76(10): 4772-4782. pdf |
| Feb 9th, 2009 | Presenter TBA pdf |
| Jan 26th, 2009 | Katherine Verbist presents Davis, J.M. and L. Ramakrishnan. 2009. The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection. Cell; 136:37-49. pdf |
| Dec 8th, 2008 | Presenter TBA |
| Nov 17th, 2008 | Charles Rosenberg presents Lundle RJ, et al. 2008. Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8a+ dendritic cells. PNAS; 105(38):14509-14514. pdf |
| Nov 3rd, 2008 | Sarah Reiff presents Milman N. et al. 2007. Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes. PNAS; 104(49): 19250-19255. |
| Oct 20th, 2008 | Josh Cole presents Dunay IR, et al. 2008. Gr1+ Inflammatory Monocytes are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii. Immunity; 29:306-317. |
| Oct 6th, 2008 | Demba Sarr presents Couper KN, et al. 2008. IL-10 from CD4+CD25-Foxp3-CD127- Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection. PLoS Pathogens; 4(2):e1000004. pdf |
| Sep 22nd, 2008 | No Presenter pdf |
| Sep 8th, 2008 | No Presenter pdf |
| Apr 14th, 2008 | Paul Ulrich Wilkinson SR, et al. 2008. A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. PNAS 105:5022-5027. pdf |
| Mar 24th, 2008 | Demba Sarr Wykes MN, et al. 2007. Plasmodium Strain Determines Dendritic Cell Function Essential for Survival from Malaria. PLoS Pathogens; 3(7):904-912. pdf |
| Mar 17th, 2008 | Sethu Nair Singh AP. 2007 Plasmodium Circumsporozoite Protein Promotes the Development of the Liver Stages of the Parasite. Cell; 131: 492-504. pdf |
| Feb 25th, 2008 | Tiffany Weinkopff Yeoh S. et al. 2007. Subcellular Discharge of a Serine Protease Mediates Release of Invasive Malaria Parasites from Host Erythrocytes. Cell. 131: 1072-1083. pdf |
| Feb 11th, 2008 | Carla Black Berhe N. et al. 2007. Intensity of Schistosoma mansoni, Hepatitis B, Age, and Sex Predict Levels of Hepatic Periportal Thickening/Fibrosis (PPT/F): A Large-Scale Community-based Study in Ethiopia. Am. J. Trop. Med. Hyg. 77(6): 1079-1086. pdf |
| Jan 28th, 2008 | Josh Cole Wolf AJ, et al. 2008. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. JEM; 205(1):105-115. pdf |
| Nov 26th, 2007 | Abhijit Bakre Bringaud F. et al. 2007. Members of a large Retroposon family are determinants of post-transcriptional gene expression in Leishmania. PLoS Pathog.;3(9):1291-307. pdf |
| Nov 12th, 2007 | Charles Rosenberg Goldszmid RS, et al. 2007. TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production.J. Exp. Med. 204: 2591-2602. pdf |
| Oct 22nd, 2007 | Sethu Nair Biswas AK, et al. 2007. Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endotherlium and for platelet-mediated clumping. PLoS Pathogens; 3(9): 1271 - 1280. pdf |
| Oct 8th, 2007 | Don Champagne Donovan MJ, et al. 2007. Uninfected Mosquito Bites Confer Protection against Infection with Malaria Parasites. Infection & Immunity; 75(5): 2523-2530. pdf |
| Sep 24th, 2007 | Demba Sarr Muehlenbachs A, et al. 2007. Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infections. The Journal of Immunology; 179: 557-565. pdf |
| Sep 10th, 2007 | Diana Martin Nagase H, et al. 2007. Despite Increased CD4+Foxp3+ Cells within the Infection Site, BALB/c IL-4 Receptor-Deficient Mice Reveal CD4+Foxp3-Negative T cells as a Source of IL-10 on Leishmania major Susceptibility. Journal of Immunology; 179:2435-2444. pdf |
| Apr 23rd, 2007 | Abhijeet Bakre Saeij JP, et al. 2006. Polymorphic Secreted Kinases are Key Virulence Factors in Toxoplasmosis. Science; 314: 1780-1783. AND Taylor S, et al. 2006. A Secreted Serine-Threonin Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii. Science; 314: 1776-1780. pdf |
| Apr 16th, 2007 | Lisa Bixby Ling YM, et al. 2006. Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. JEM; 203(9): 2063 - 2071. pdf |
| Apr 2nd, 2007 | Laura Cliffe Zaph C, et al. 2007. Epithelial-cell-intrinsic IKK-B expression regulates intestinal immune homeostasis. Nature; Epublished Feb. 25. pdf |
| Mar 19th, 2007 | Andrea Pruijssers Dunne EF, et al. 2007. Prevalence of HPV infection among females in the United States. JAMA; 297(8):813-819. pdf |
| Mar 5th, 2007 | Christie Harwell Awandare GA, et al. 2007. Role of Monocyte-Acquired Hemozoin in Suppression of Macrophage Migration Inhibitory Factor in Children with Severe Malarial Anemia. IAI; 75(1):201-210. pdf |
| Feb 19th, 2007 | Tiffany Weinkopff Yurchenko E, et al. 2006. CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence. JEM; 203(11):2451-2460. pdf |
| Feb 5th, 2007 | Roberto Docampo Piacenza L, et al. 2006. Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial Fe-superoxide dismutase overexpression. Biochemical Journal. AND Prathalingham SR, et al. 2007. Deletion of the Trypanosoma brucei Superoxide Dismutase Gene sodb1 Increases Sensitivity to Nifurtimox and Benznidazole. Anitmicrobial Agents and Chemotherapy; 51(2):755-758. pdf1 pdf2 pdf |
| Jan 22nd, 2007 | Carla Black Atika, B. et al. 2006. Impact of Annual Targeted Treatment on Infectious Trachoma and Susceptibility to Reinfection. JAMA; 296(12):1488-1497 pdf |
| Jan 8th, 2007 | |
| Dec 4th, 2006 | Charles Rosenberg Cobb BS, et al. 2006. A role for Dicer in immune regulation. J. Exp. Med. 203:2519-2527 pdf |
| Nov 20th, 2006 | Angel Padilla Bertholet S, et al. 2006. Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo. J Immunol. 177: 3525-3533 pdf |
| Nov 6th, 2006 | David Peterson Mair GR, et al. 2006. Regulation of Sexual Development of PLASMODIUM by Translation Repression. Science; 313: 667-669. pdf |
| Oct 23rd, 2006 | Sethu Nair Felix Yarovinsky et al. Toll-like Receptor Recognition Regulates Immunodominance in an Antimicrobial CD4+ T Cell Response, IMMUNI (2006), doi:10.1016/j.immuni.2006.07.015 pdf |
| Oct 9th, 2006 | Matthew Collins Singh SB, et al. 2006. Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria. Science; 313:1438-1441. pdf |
| Sep 25th, 2006 | Silvia Moreno Soo Hee Lee, et al. 2006. Fatty Acid Synthesis by Elongases in Trypanosomes. Cell; 126:691-699. pdf |
| Sep 11th, 2006 | Juan Bustamante Baral TN, et al. 2006. Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor. Nature Medicine; 12(5): 580-584. pdf |
| Aug 28th, 2006 | Jan Schwenkenbecher Lehmann T. et al. 2006. Globalization and the population structure of Toxoplasma gondii. PNAS; 103(30):11423-11428. pdf |
| May 1st, 2006 | Sethu Nair Baumeister S. et al. 2006. Evidence for the involvement of Plasmodium falciparum proteins in the formation of new permeability pathways in the erythrocyte membrane. Molecular Microbiology; 60(2): 493-504. pdf |
| Apr 17th, 2006 | Lisa Bixby Polley R. et al. 2005. Chronic Leishmania donovani Infection Promotes Bystander CD8+ T-cell Expansion and Heterologous Immunity. Infection and Immunity; 72(2): 7996-8001. pdf |
| Apr 3rd, 2006 | Charles Rosenberg Tumpey, TM. 2005. Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice. Journal of Virology; 79(23):14933-14944. pdf |
| Mar 20th, 2006 | Dan Xu Suffia IJ, et al. 2006. Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens. JEM. 203(3):early release. pdf |
| Mar 6th, 2006 | Anja T. R. Jensen SPECIAL SEMINAR: "Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by Group A var genes" pdf |
| Feb 20th, 2006 | Carly Jordan Molestina RE and AP Sinai. 2005. Host and parasite-derived ILL activities direct distinct temporal phases of NF-kB activation and target gene expression following Toxoplasma gondii infection. Journal Cell Science 118:5785-5796. pdf |
| Feb 6th, 2006 | Tiffany Weinkopff Dann SM, et al. 2005. Interleukin-15 Activates Human Natural Killer Cells to Celar the Intestinal Protozoan Cryptosporidium. JID 192:1294-1302. pdf |
| Jan 23rd, 2006 | Diana Martin Baum, J. et al. 2005. Invasion by P. falciparum Merozoites Suggests a Hierarchy of Molecular Interactions. PLoS Pathogens, 1(4)e37:299-309. pdf |
| Jan 9th, 2006 | Boris Striepen pdf |
| Dec 5th, 2005 | Jessica Kissinger Martens S, et al. 2005. Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases. PLoS Pathogens; 1(3)e24:0187-0201. pdf |
| Nov 21st, 2005 | Giel van Dooren Li W, et al. 2005. Yeast model uncovers dual roles of mitochondria in the action of artemisinin. PLoS Genetics, 1(3):e36. pdf |
| Nov 7th, 2005 | Nandita Mullapudi Callebaut I, et al. 2005. Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes. BMC Genomics; 6(100): 1-20. pdf |
| Oct 24th, 2005 | Naomi Lucchi Chamekh M, et al. 2005. Transfection of Trypanosoma cruzi with Host CD40 Ligand Results in Improved Control of Parasite Infection. Infection and Immunity, 73(10):6552-6561. pdf |
| Oct 10th, 2005 | Valerie Gordon Kariminia A, et al. 2005. Transforming Growth Factor B1 Production by CD4+ CD25+ Regulatory T Cells in Peripheral Blood Mononuclear Cells from Healthy Subjects Stimulated with Leishmania guyanensis. Infection and Immunity; 73(9): 5908-5914. pdf |
| Sep 26th, 2005 | Matt Collins Bian, KA, et al. 2005. Helminth regulation of host IL-4Ra/Stat6 signaling: Mechanism underlying NOS-2 inhibition by Trichinella spiralis. PNAS, 702 (11): 3036-3041. pdf |
| Sep 12th, 2005 | Rick Tarleton Stober CB, et al. IL-10 from Regulatory T Cells Determines Vaccine Efficacy in Murine Leishmania major Infection. J Immunol. 2005 Aug 15;175(4):2517-24. AND Wykes MN, et al. Plasmodium yoelii Can Ablate Vaccine-Induced Long-Term Protection in Mice. J Immunol. 2005 Aug 15;175(4):2510-6. pdf |
| Aug 29th, 2005 | Shipra Vaishnava Ramamoorthi N. et al. 2005. The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature; 436: 573-577. pdf |
| Apr 18th, 2005 | Marc-Jan Gubbels Charron AJ and LD Sibley. 2004. Molecular Partitioning during Host Cell Penetration by Toxoplasma gondii. Traffic; 5:855-867. pdf |
| Apr 4th, 2005 | Lisa Sharling Figueiredo LM , et al. (2005) The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus. Nucleic Acids Research; 33(3):1111-1122. pdf |
| Mar 21st, 2005 | Josh Kotner Mueller, AK, et al. 2005. Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature, 433: 164-167. pdf |
| Mar 7th, 2005 | Jessica Kissinger Loftus B, et al. 2005. The genome of the protist parasite Entamoeba histolytica. Nature, 433: 865-868. pdf |
| Feb 21st, 2005 | Jayakumar Poovassery Brustoski K, et al. 2005. IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria. Journal of Immunology, 175:1738-1745. pdf |
| Feb 7th, 2005 | Jolly Mazumdar Hiller NL, et al. 2004. A Host-Targeting Signal in Virulence Proteins Reveals a Secretome in Malarial Infection. Science;306:1934-1937. pdf |
| Jan 24th, 2005 | Dan Colley Oriss TB, et al. 2005. Dynamics of Dendritic Cell Phenotype and Interactions with CD4+ T Cells in Airway Inflammation and Tolerance. J. Immunol.;174:854-863. pdf |
| Jan 10th, 2005 | Diana Martin Coban C, et al. 2005. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. JEM. 201(1):19-25. pdf |
| Dec 6th, 2004 | Boris Striepen Engstler M and M Boshart. 2004. Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei. Genes & Development, 18:2798-2811. pdf |
| Nov 22nd, 2004 | Rick Tarleton Nitz N, et al. 2004. Heritable Integration ofkDNA Minicircle Sequences from Trypanosoma cruzi in to the Avian Genome: Insights into Human Chagas Disease. Cell, 118:175-186. pdf |
| Nov 8th, 2004 | Nandita Mullapudi Coulson RMR, et al. 2004. Comparative genomics of transcriptional control in the human malaria parasite Plasmodium falciparum. Genome Research, 14: 1548-1554. pdf |
| Oct 25th, 2004 | David Peterson Gamain B, et al. 2004. Identification of a 67-amino-acid region of the Plasmodium falciparum variant surface antigen that binds chondroitin sulphate A and elicits antibodies reactive with the surface of placental isolates. Molecular Microbiology, 53(2): 445-455. pdf |
| Oct 11th, 2004 | Becky Bundy Koski G, et al. 2004. Cutting Edge: Innate immune aystem discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells. Journal of Immunology. 172:3989-3993. pdf |
| Sep 27th, 2004 | Marc-Jan Gubbels Blandin S, et. al. 2004. Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae. Cell, 116: 661-670. pdf |
| Sep 13th, 2004 | Naomi Lucchi Pouniotis DS, et al. 2004. Dendritic cells induce immunity and long-lasting protection against blood-stage malaria despite an in vitro parasite-induced maturation defect. Infection and Immunity, 72(9): 5331-5339 pdf |
| Apr 19th, 2004 | Jinling Huang Osta MA, et al. 2004.Effects of Mosquito Genes on Plasmodium Development. Science, 303: 2030-2032. pdf |
| Apr 5th, 2004 | Naomi Lucchi Cockburn IA, et al. 2004. A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria. PNAS, 101(1): 272-277. pdf |
| Mar 22nd, 2004 | Dan Colley Cervi L, et al. Cutting Edge: Dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific TH2 repsonses. J.Immunol. 2004 Feb 15;172(4):3016-20. pdf |
| Feb 23rd, 2004 | Diana Martin Moody DB, et al. 2004. T Cell Activation by Lipopeptide Antigens. Science, 303:527-531 pdf |
| Feb 9th, 2004 | Jayakumar Poovassery Fallarino F, et al. 2003. Modulation of tryptophan catabolosm by regulatory T cells. Nature Immunology, 4(12): 1206-1212. pdf |
| Jan 26th, 2004 | Marc-Jan Gubbels Coppens I and KA Joiner. 2003. Host but not parasite cholesterol controls Toxoplasma cell entry by modulating organelle discharge. Molecular Biology of the Cell, 14:3804-3820. pdf |
| Jan 12th, 2004 | Shipra Vaishnava Relict mitochondrions of Giardia and Cryptosporidium pdf |
| Dec 1st, 2003 | Josh Kotner Vanhamme L, et al. 2003. Apolipoprotein L-1 is the trypanosome lytic factor of human serum. Nature, 422:83-87. pdf |
| Nov 17th, 2003 | Jessica Kissinger Dueling Techniques - The Plasmodium transcriptome revealed (part II) pdf |
| Nov 3rd, 2003 | Nandita Mullapudi Dueling Techniques - The Plasmodium transcriptome revealed (part I) pdf |
| Oct 20th, 2003 | Rick Tarleton Yan Shi et al. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature, 425: 516-521. pdf |
| Oct 6th, 2003 | Becky Bundy Doench JG, et al. 2003. siRNAs can function as miRNAs. Gene & Development, 17:438-442. pdf |
| Sep 22nd, 2003 | Kanji Watanabe Miniature pigs as a highly susceptible experimental model for Schistosoma japonicum infection pdf |
| Sep 8th, 2003 | David Morrison U. Eckstein-Ludwig, et al. 2003. Artemisinins target the SERCA of Plasmodium falciparum. Nature, 424: 957-961. pdf |
| Aug 25th, 2003 | Julie Moore David McDonald, et al. 2003. Recruitment of HIV and its receptors to dendritic cell-T-cell junctions. Science, 300:1295-1297 pdf |
| Apr 21st, 2003 | Becky Bundy Serikawa KA, et al. (2003) The transcriptome and its translation during recovery from cell-cycle arrest in Saccharomyces cerevisiae. MCP papers in press. pdf |
| Apr 7th, 2003 | Chitra Thadhani Stedman TT, et al. Toxoplasma gondii Rab6 Mediates a Retrograde Pathway for Sorting of Constitutively Secreted Proteins to the Golgi Complex. Journal of Biological Chemistry, 14 Feb 2003;278(7):5433-5 pdf |
| Mar 24th, 2003 | Alison Nairn Gaunt MW, et al. Mechanism of genetic exchange in American trypanosomes. Nature, 27 Feb 2003;421:936-939 pdf |
| Mar 10th, 2003 | Paul Drummond Miller SK, et al. A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle. J. of Biological Chemistry, 6 Dec 2002;277(49):47524-47532 pdf |
| Feb 24th, 2003 | Jayakumar Poovassery Hannaert V, et al. Plant-like traits associated with metabolism of Trypanosoma parasites. PNAS, Feb. 2003;100(3):1067-1071 pdf |
| Feb 10th, 2003 | Jennifer Gibson Huston CD, et al. Apoptotic Killing and Phagocytosis of Host Cells by the Parasite Entamoeba histolytica. Infection and Immunity, Feb 2003;71(2):964-972. pdf |
| Jan 27th, 2003 | Diana Martin Amelie v. Saint Andre, et al. The Role of Endosymbiotic Wolbachia Bacteria in the Pathogenesis of River Blindness. 8 March 2002;295:1892-1895. pdf |
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| Dec 31st, 1969 | TBA pdf |










